Search on: 15-OXOPROSTAGLANDIN 13-REDUCTASE 
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Descriptor English:   15-Oxoprostaglandin 13-Reductase 
Descriptor Spanish:   15-Oxoprostaglandina 13-Reductasa 
Descriptor Portuguese:   15-Oxoprostaglandina 13-Redutase 
Synonyms English:   Prostaglandin delta-13-Reductase
Prostaglandin-13,14-Reductase  
Tree Number:   D08.811.682.660.490
Definition English:   (5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. EC 1.3.1.48. 
Indexing Annotation English:   DF: OXOPG REDUCTASE
History Note English:   94; was PROSTAGLANDIN-13,14-REDUCTASE 1978-93 (see under OXIDOREDUCTASES 1978-90); DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE was (NM) 1976-93; PROSTAGLANDIN DELTA 13 REDUCTASE was (NM) 1981-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   31899 
Unique Identifier:   D011452 

Occurrence in VHL:
 

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